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What Are Polynucleotides? The Skin Booster Everyone’s Talking About

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At HAVA Aesthetics in Esher, Surrey, we’re always focused on advanced treatments that deliver natural, healthy, and long-lasting skin rejuvenation. One of the most talked-about innovations in modern aesthetics right now is Polynucleotides, regenerative injectables designed to improve skin quality from within.

If you’ve been hearing about them online or from skincare experts and are wondering exactly what they do, this guide explains what polynucleotides are, how they work, and why they’ve quickly become one of the most sought-after skin booster treatments available today.

What Are Polynucleotides?

Polynucleotides are biostimulatory molecules derived from fragments of DNA, most commonly extracted from purified, sterile sources of salmon DNA, known for their exceptional compatibility with human tissue. When injected into the skin, they trigger deep skin regeneration, improving hydration, elasticity, and texture over time.

Unlike traditional dermal fillers, which focus on adding volume, polynucleotide treatments stimulate your body’s natural repair processes. They work at a cellular level, activating fibroblasts, the cells responsible for collagen and elastin production, while improving oxygen supply and reducing inflammation.

The result is visibly healthier, smoother, and more luminous skin that continues to improve long after your treatment session.

How Do Polynucleotides Work?

When injected into the skin, polynucleotides interact with the body’s natural cell regeneration pathways. They encourage cell turnover, restore hydration, and improve the structure of the extracellular matrix, which supports firmness and elasticity.

This process helps to:

  • Boost collagen and elastin synthesis for firmer, tighter skin.
  • Enhance skin hydration by increasing water retention in the dermal layer.
  • Stimulate tissue repair, aiding recovery from sun damage and scarring.
  • Calm inflammation and protect against oxidative stress, a key cause of premature ageing.

At HAVA Aesthetics, Dr Hadeel Nimaa uses high-quality Polynucleotide injectables that have been clinically developed for safety and long-term efficacy. These bioregenerative treatments are suitable for a wide range of patients and skin concerns, from fine lines and dullness to early signs of ageing and loss of firmness.

What Can Polynucleotides Treat?

Polynucleotides are incredibly versatile and can be used across multiple areas of the face and body. They are especially effective for treating:

  • Fine lines and wrinkles
  • Under-eye hollows and dark circles
  • Dehydrated or tired-looking skin
  • Mild sagging or loss of elasticity
  • Sun-damaged or inflamed skin
  • Acne scarring and texture irregularities

They can be performed as a standalone treatment or combined with other skin boosters and microneedling sessions for enhanced rejuvenation. Many patients also choose to pair them with hyaluronic acid-based treatments or anti-wrinkle injections for comprehensive facial revitalisation.

What to Expect During Treatment

Your Polynucleotide treatment begins with a consultation and full skin assessment with Dr Hadeel Nimaa to understand your goals and determine the best approach for your skin.

During the procedure, a topical numbing cream is applied to ensure comfort. Small amounts of the polynucleotide gel are then carefully injected into the chosen areas using precise microinjection techniques. Treatment typically takes around 30 to 45 minutes, depending on the area being treated.

Because the treatment focuses on deep cellular regeneration rather than surface-level correction, results develop gradually over the following weeks. You’ll notice improved radiance and hydration first, followed by smoother texture and enhanced firmness as new collagen and elastin form.

How Long Do Results Last?

Results from Polynucleotide injections are long-lasting, typically remaining visible for six to twelve months depending on your skin type, age, and lifestyle.

For the best outcome, Dr Hadeel Nimaa often recommends a course of two to three sessions, spaced a few weeks apart. This allows the skin to build strength and resilience naturally, with results that continue to evolve over time. Maintenance sessions can then be scheduled every six to twelve months to preserve that healthy, refreshed glow.

Why Choose Polynucleotides Over Traditional Skin Boosters?

While both skin booster treatments and polynucleotide injectables aim to improve skin quality, polynucleotides go deeper. Instead of simply hydrating the skin, they encourage regeneration within the dermal tissue, repairing and strengthening it from the inside out.

Key advantages include:

  • Stimulates long-term collagen production for lasting firmness.
  • Improves skin texture and tone without adding volume.
  • Reduces inflammation and oxidative stress for calmer, clearer skin.
  • Safe for all skin types, including sensitive or compromised skin.

This makes polynucleotides an excellent option for patients seeking natural, restorative rejuvenation without altering their facial structure.

Why Choose HAVA Aesthetics in Surrey

At HAVA Aesthetics, every Polynucleotide treatment is performed by Dr Hadeel Nimaa, an experienced medical aesthetics practitioner with a deep understanding of skin biology and facial anatomy.

We focus on achieving subtle, regenerative, and long-lasting improvements, using only premium medical-grade products within a safe, professional environment. Each treatment plan is tailored to your skin concerns, ensuring your results are natural, balanced, and aligned with your overall aesthetic goals.

Book Your Consultation

If you’ve been wondering “What are polynucleotides?” or are curious about how they can transform your skin, our expert team at HAVA Aesthetics is here to help.

Contact us today to book your consultation with Dr Hadeel Nimaa and discover why polynucleotides are the skin booster everyone’s talking about.

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HAVA Aesthetics Esher
Health Village Esher, 13-17 Church Street,
Esher, Surrey, KT10 8QS
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HAVA Aesthetics Harley Street London
2 Harley Street, London, W1G 9PA
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