Treatments
Polynucleotides Surrey
Medically reviewed by Dr Hadeel Nimaa, MBChB, MRCGP
GMC: 7149019
Last reviewed 14 October 2026 · Next review 14 April 2027
Treatment Overview
Polynucleotides are advanced regenerative injectable treatments used in modern skin rejuvenation therapy to repair and strengthen ageing or damaged skin tissues from within.
Derived from highly purified DNA fragments (commonly PDRN sourced from salmon DNA), polynucleotides stimulate fibroblast activity, increase collagen production, improve skin elasticity, and support long-term cellular repair.
At HAVA Aesthetics in Esher, Surrey, polynucleotide treatments are used to restore skin tone, improve uneven skin texture, reduce pigmentation issues, and strengthen sagging or thinning skin without adding volume.
Unlike dermal fillers, this treatment focuses purely on regeneration, enhancing structural integrity rather than altering facial contours.
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At a glance
Price
From £350 per area
Treatment time
30 - 45 minutes
Downtime
Minimal
Results Last
Up to 9 months
Practitioner
Dr Hadeel Nimaa
Location
Esher, Surrey
Treatments
Before & After
See the difference Polynucleotides Surrey
has made for our clients
How Do Polynucleotides Work?
Once delivered into carefully selected injection sites within the dermis, polynucleotides:
- Stimulate fibroblast activity
- Increase collagen and elastin synthesis
- Improve microcirculation
- Repair damaged skin tissues
- Reduce inflammation
- Strengthen the skin barrier
- Support recovery from UV rays and environmental damage
This biological response gradually improves skin elasticity, resilience and overall tone. Rather than temporarily hydrating the skin, polynucleotides promote genuine tissue regeneration.
Benefits of Polynucleotide Treatment
Polynucleotides are ideal for patients seeking regenerative skin improvement rather than adding structural volume. This treatment works to strengthen and repair the skin from within, improving overall skin quality and resilience.
Benefits include improved skin tone and radiance, reduction in uneven skin tone and texture, enhanced elasticity, and softening of fine lines and wrinkles. Polynucleotides can also help improve acne scars, reduce visible pigmentation concerns, support thinning or fragile skin, and improve mild skin laxity by strengthening skin tissues.
This treatment is suitable for a wide range of skin types, particularly ageing, sun-damaged, or compromised skin requiring restoration and long-term skin health support.
Polynucleotides vs Profhilo
Both are injectable skin treatments, but they work differently. Profhilo is a hyaluronic acid bio-remodelling treatment that hydrates and gives a temporary firming effect. Polynucleotides go further, using purified DNA fragments (PDRN) to stimulate genuine tissue regeneration and collagen repair, improving skin strength and quality over the longer term. Dr Hadeel Nimaa will advise which suits your skin at your consultation.
Polynucleotides Under-Eye Treatment
Polynucleotides under eyes are one of the most popular uses of this treatment, working as an advanced under-eye rejuvenation option.
They help improve:
- Thin or crepey skin
- Fine lines
- Dark circles linked to thinning tissue
- Early laxity
Unlike tear trough filler, polynucleotides improve skin quality without adding volume, making them ideal for delicate areas prone to swelling or irregularity.
Polynucleotides for Acne Scars & Pigmentation Issues
Polynucleotide therapy is highly effective for:
- Acne scars
- Textural irregularities
- Post-inflammatory pigmentation issues
- Sun damage caused by UV rays
- Uneven Skin Tone
By stimulating collagen remodelling, this regenerative treatment smooths uneven texture and strengthens damaged skin tissues.
Who Is Suitable for Polynucleotide Treatment?
Polynucleotides are suitable for patients experiencing fine lines and wrinkles, sagging skin, dullness or dehydration, uneven skin tone or texture, acne scars, early signs of ageing, or a compromised skin barrier. They are particularly beneficial for those who do not require volume enhancement but wish to improve overall skin quality and support structural skin repair.
During your consultation, we carefully assess your skin condition, concerns, and full medical history to determine suitability. While polynucleotides are appropriate for many patients, they may not be recommended for individuals with active skin infections or certain inflammatory skin conditions. These factors are thoroughly screened to ensure treatment is both safe and effective.
The Treatment Process
Average Treatment Time: 30–45 minutes.
Your treatment begins with a detailed medical consultation to determine appropriate injection sites and treatment areas.
Using fine needles, polynucleotides are placed strategically within the dermis to stimulate regeneration.
A course of three sessions spaced four weeks apart is typically recommended.
You will receive detailed post-care instructions following treatment to optimise results and reduce risk of irritation.
A review appointment is scheduled to assess progress and determine whether additional sessions are required.
Downtime & Side Effects
Polynucleotide treatments are minimally invasive with limited downtime.
You may experience:
- Mild swelling
- Redness
- Small injection marks
- Temporary tenderness
These effects typically resolve within a few days.
Patients are advised to:
- Avoid intense heat or sun exposure
- Avoid strenuous activity for 24–48 hours
- Protect the skin from UV rays
Duration of Results
The duration of results varies depending on factors such as age, lifestyle, skin condition, and overall skin health at the time of treatment. Individual regenerative capacity and adherence to aftercare can also influence how long improvements are maintained.
Most patients experience visible improvement lasting up to 9 months, with a course of treatments typically recommended for optimal outcomes. Maintenance sessions can help extend and reinforce the regenerative benefits, supporting long-term skin quality and resilience.
Hydration and skin luminosity often improve in the early weeks following treatment, while collagen stimulation develops gradually over several weeks. As the skin regenerates from within, texture, firmness, and overall tone continue to refine, creating natural, progressive enhancement.
How Much Do Polynucleotides Cost in Surrey?
Polynucleotide treatment at HAVA Aesthetics starts from £350 per area. Because polynucleotides work best as a course, usually three sessions spaced four weeks apart, your full plan and cost are confirmed at your consultation with Dr Hadeel Nimaa, based on the areas treated (such as the face, under-eyes or neck). See our full price list for details.
Polynucleotide Guides
Want to know more before you book? Read our guides to how long polynucleotides last, how long they take to work, polynucleotides under the eyes, polynucleotides vs Profhilo, polynucleotides vs skin boosters, microneedling vs polynucleotides and what polynucleotides cost in Surrey.
Why Choose HAVA Aesthetics in Esher, Surrey?
HAVA Aesthetics is a leading cosmetic clinic for regenerative and non-surgical aesthetic treatments across Surrey, including Kingston, Epsom, Thames Ditton, Cobham and Weybridge.
Led by Dr Hadeel Nimaa, our medical-led approach ensures safe, precise and personalised treatment planning. We combine polynucleotides with other aesthetic treatments where appropriate, including dermal fillers and Injectables for Wrinkles, to create comprehensive rejuvenation plans.
If you are experiencing sagging skin, uneven tone, acne scars or early ageing signs, polynucleotide skin rejuvenation therapy may be an ideal solution. Schedule a Consultation at our Esher clinic to receive a personalised assessment and treatment plan.
Regulated, Doctor-Led Care
Your polynucleotide treatment is planned and carried out by Dr Hadeel Nimaa, and you can check her credentials for yourself.
- Treatment carried out by Dr Hadeel Nimaa, a doctor registered with the General Medical Council (GMC 7149019)
- Member of the Save Face register of accredited practitioners
- Full medical consultation before every treatment
- Clear pricing: polynucleotides from £350 per area, see our price list
Are Polynucleotides Safe?
Polynucleotides are a well-established injectable skin treatment when carried out by a trained, regulated medical practitioner. At HAVA Aesthetics, every treatment is planned and performed by Dr Hadeel Nimaa (GMC 7149019), and you will have a full medical consultation before anything is injected.
Risks and possible side effects
Most side effects are mild and settle within a few days. They can include redness, swelling or tenderness at the injection points, small bruises or lumps that usually soften and fade within days, itching or a warm feeling in the skin, and, rarely, an allergic reaction, an infection or a cold sore flare-up.
What to do if something feels wrong
Contact the clinic on 0344 967 0003 if swelling, pain or redness is getting worse after the first few days, if you develop a temperature, or if the skin looks unusually pale, dusky or blistered. Do not wait for your next appointment.
Who should not have polynucleotides
Treatment may not be suitable if you are pregnant or breastfeeding, have an allergy to fish or salmon products (many polynucleotides are made from salmon DNA), have an active skin infection, cold sore or inflamed skin in the area to be treated, have a bleeding disorder or take medicines that thin the blood, or have an autoimmune condition or are unwell on the day.
Dr Nimaa will go through your medical history with you and will tell you honestly if another treatment would suit you better.
Treatment
Frequently asked questions
How much do polynucleotide treatments cost in Surrey?
Polynucleotide treatments start from £350 per area. A course of three sessions is usually recommended, and your exact cost is confirmed at your consultation depending on the areas treated.
Are polynucleotides worth it?
Polynucleotides can be worth considering if you want to improve skin quality without adding facial volume. They work by stimulating fibroblast activity, collagen and elastin production to support skin repair, helping to improve fine lines, elasticity, texture, hydration and overall skin resilience. Results develop gradually and can last up to nine months following a recommended treatment course.
How many sessions of polynucleotides will I need?
A course of three polynucleotide treatment sessions, typically spaced around four weeks apart, is usually recommended for optimal results. Your treatment plan may vary depending on your skin condition, concerns and treatment area. A review appointment can then determine whether additional or maintenance sessions would be beneficial.
Can anyone have polynucleotide treatment?
Polynucleotides are suitable for a wide range of patients and skin types, particularly those experiencing fine lines, dullness, uneven texture, acne scarring, early skin laxity or other signs of ageing. However, treatment may not be appropriate for people with active skin infections or certain inflammatory skin conditions. At HAVA Aesthetics, your medical history and skin condition are assessed during consultation to confirm that treatment is suitable for you.
Does polynucleotide treatment hurt?
Most people describe a mild pinch or a stinging feeling as the fine needle goes in. A numbing cream can be applied beforehand, and the whole treatment takes around 30 to 45 minutes.
Are there any side effects to polynucleotides?
Common effects are redness, mild swelling, small bumps and occasional bruising at the injection points, which usually settle within a few days. Dr Nimaa will go through all possible risks with you at your consultation.
Are polynucleotides safe?
Yes, when performed by a trained and regulated medical professional after a proper consultation. At HAVA, treatment is carried out by Dr Hadeel Nimaa (GMC 7149019). Your suitability is checked first, and she explains the risks and aftercare before you decide to go ahead.
What aftercare is required?
Yes. Aftercare advice includes avoiding strenuous activities and excessive sun exposure for 24–48 hours. Do not touch or massage the treated area and follow your practitioner’s guidance to optimise results. Normal activities can usually resume the day after treatment.
When will I see results, and how long will they last?
Improvements may be noticed after the initial session, with a youthful complexion and skin hydration becoming more apparent as treatment progresses. With a full course, results can last up to 9 months. Touch-up treatments and a maintenance session are recommended for long-term benefits.
Are polynucleotides good for under eyes?
Yes. Polynucleotides under eyes improve thin, crepey skin, fine lines and dark circles linked to thinning tissue, without adding volume, making them a gentle option for the delicate under-eye area.
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What our patients say...
Dr Hadeel is always very professional and knowledgeable in respect of all the procedures she offers but is also very approachable and understanding.
She is a true professional and never pressurises one into making a hurried decision but will discuss the results one can realistically expect. I am happy to recommend Dr Hadeel to my family and friends. I intend seeking further advice and treatments from her as I have every confidence in her abilities.
Sue
Highly recommend Dr Hadeel. Warm, professional with great skills and advice. She focuses on natural results and supporting you through the process.
Joanne
Dr Hadeel Nimaa discussed with me prior to my procedure what I wanted; my questions were fully answered.
I had treatments on my cheeks, chin and lips. She made me feel at ease and I also felt very relaxed during the treatment. I would highly recommend Dr Hadeel Nimaa as I am very pleased with the results and it has given me more confidence looking and feeling so good.
Cim
Dr Hadeel does my treatments; she is friendly and welcoming. She always explained the procedure and what to expect, always happy with the treatments received. Can’t recommend enough.
Maria
I have had a number of skin treatments with Dr Hadeel, the latest one being HarmonyCa skin booster.
Dr Hadeel has not only provided treatments which have always proved to have excellent results but she has also as importantly always made sure that I have been 100% comfortable and knowledgeable about each treatment before going ahead. In the three plus years she has been treating me, I have never been anything but delighted with the results.
Geri